Endothelin-1 Mediates Brain Microvascular Dysfunction Leading to Long-Term Cognitive Impairment in a Model of Experimental Cerebral Malaria.
Plasmodium falciparum infection causes a wide spectrum of diseases, Campping Beds including cerebral malaria, a potentially life-threatening encephalopathy.Vasculopathy is thought to contribute to cerebral malaria pathogenesis.The vasoactive compound endothelin-1, a key participant in many inflammatory processes, likely mediates vascular and cognit